Patients Can Now Partner with Healthcare Providers to Avoid Adverse Drug Reactions (ADRs) with RxWise™, the First Consumer-Friendly, Portable Medication Safety Checking System

Via Web or USB Flash Drive, RxWise™ Analyzes an Individual's Prescription, Over-the-Counter and Herbal Medicines together with their Personal Medical History and Reports Potential ADR Risks

Herndon, VA, July 20, 2005 — Iatrogen, LLC, the bioinformatics leader in products and services that enable patients to partner with their healthcare providers to use medicines more safely, announced today the launch of RxWise ™, the first personalized, adverse drug reaction (ADR) risk-assessment system contained on a portable USB Flash Drive, or accessible through the Internet.

RxWise evaluates the potential risks for an ADR by analyzing a patient's individual medical history or insurance claims-based information and checking it against medications they are taking. Using sophisticated risk-assessment software, RxWise provides important, personalized information about medications that may cause an adverse reaction. The product covers a broad range of prescription, herbal and over-the-counter drugs.

With pull-down windows, consumers can easily record their medical information and create a history of specific drugs they are taking and medical conditions they have, as well as their known drug allergies. Once the information is entered into RxWise, a summary of relevant advisories regarding potential risks will be immediately displayed.

"We are seeing a growing number of ADRs reported, medications recalled, and consumers and healthcare providers increasingly concerned about the safety of even over-the-counter medications," said M. Lee Morse, President and Co-founder of Iatrogen. Our system is the first of its kind and empowers patients to partner with their healthcare providers to use medicines more safely," said Morse.

"The use of prescription, non-prescription and herbal medicines is more prevalent than ever and everyone can react differently to the same medication," said Aida LeRoy, Pharm.D., Executive Vice President and Co-founder, Iatrogen. "RxWise not only encourages a dialogue between healthcare providers and their patients, but provides an affordable solution to this growing problem," said LeRoy.

Adverse Drug Reactions—A Well Documented Danger

• ADRs are reportedly linked to the deaths of as many as 100,000 hospitalized patients each year in the U.S.
• ADRs are the fourth to sixth leading cause of death in the U.S. each year, ahead of pulmonary disease, diabetes, AIDS, pneumonia, accidents and automobile deaths.
• As many as 4 million people in the U.S. annually experience serious, non-fatal ADRs.
• ADRs cause one out of five injuries or deaths per year to hospitalized patients.

RxWise is a solution to the pervasive ADR problem. The RxWise USB Flash Drive is available for $39.95. The RxWise Web version, accessible through the Internet, is available for $24.00. Both can be purchased at www.rxwise.com.

RxWise was developed by the United States' leading ADR avoidance team. More than 20 million patients have been protected by this team's technologies. The design team was a past winner of the Smithsonian Award for best IT in Medicine for its ADR avoidance system. The RxWise team has built and operated ADR avoidance/detection systems for over a dozen U.S. state health systems, the U.S. Food and Drug Administration, the Department of Defense, the Veterans Administration, Blue Cross and Blue Shield, and large employer groups including General Motors, Ford Motor Company, Chrysler, Goodyear and the Boeing Company, and many others.

About Iatrogen
Iatrogen, LLC is the bioinformatics leader in products and services that enable consumers to use medicines more safely. Iatrogen evolved from the combined 50 years of experience of its founders in the clinical health and pharmaceutical outcomes industry. Located just outside Washington, DC in Herndon, Virginia, Iatrogen is composed of a team of highly qualified and experienced clinical pharmacists, epidemiologists, software designers, and IT professionals who manage the ongoing development and administration of the company's web and USB Flash Drive-based consumer products. For more information, visit http://www.rxwise.com.