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Medication safety is an issue of mounting importance for physicians, consumers, health plans and self-insured employers. As a physician, you understand the significant constraints adverse drug reactions (ADRs) impose on healthcare and productivity outcomes.

RxWise empowers physicians and consumers by identifying potentially serious ADR risks through analysis of a patient's self-reported medical conditions and medication use against thousands of ADR risk markers. RxWise also analyzes important risks related to over-the-counter and herbal products—medications typically not addressed by pharmacy based point-of-sale or web-based drug interaction checker tools. Working in concert with physicians, patients, and their healthcare providers, RxWise can help avoid many potentially serious ADRs.

RxWise is the result of established pharmaco-epidemiologic methods for assessing medication safety, and Iatrogen's 25 years of ADR avoidance design experience. Over the years, our risk assessment technology has provided precautionary alerts for over 20 million patients. Additionally, it won the Smithsonian Award for Information Technology in Medicine, and is now a permanent part of the IT archive of the Smithsonian Museum of American History. Our pharmaco-epidemiologic rules were developed over the past two decades by Iatrogen's clinical and biostatistics staff to assess the causal link between pharmaceutical exposure and subsequent unintended outcomes. Under contract to the FDA for over a decade, Iatrogen analyzed predisposing predictive factors such as age, sex, current medical history and concomitant drug use for their potential contribution to an ADR.

Precise Prescriptions

Presently, physicians need to largely rely on information about a broad population's average drug response to predict therapeutic outcomes for their individual patients.

Today's patients typically visit multiple healthcare providers, and take four or more medicines at any given time. Through the analysis of a patient's medical history and pharmaceutical use profile, physicians will be better able to prescribe the best available drug therapy. The many benefits include more effective treatment, increased safety, speedier recoveries, and higher patient and physician satisfaction. RxWise empowers physicians by helping them make more informed prescribing decisions through the incorporation of their patients' disease and drug use information.

More Informed Prescribing

An individual disease/drug use profile, which includes a patient's over-the-counter and herbal drug use, can provide physicians with better information to optimize therapy.

Reduced Costs

Healthcare costs are skyrocketing. In a recent survey of 2,800 employers by William M. Mercer, a human resources consulting firm, the average increase in healthcare benefits cost per employee rose 11.2% in 2001—the largest increase in 9 years! A recent study estimated that total healthcare spending doubled between 1995 and 2000 (Journal of the American Pharmaceutical Association, 2001, March-April;41(2)). Another study reported that severe ADRs resulted in excess of $4 billion in annual healthcare costs. (Clin. Chim. Acta., 2002; January; 315(1-2)137-55).

With a personalized drug therapy that fully reflects your patients' complete disease and drug use history, preventable spending on ADRs will likely decrease. Additionally, easily accessible patient medical profiling is expected to play an increasingly vital role in reducing treatment failures and ADRs.

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Last update: 04/25/2006
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